What a tough question! Who knew there was such a thing as "early puppyhood" and "middle puppyhood." In my mind these stages all existed in a simple, single stage known as "puppy stage."
I picked E, but let me see and strongly considered D, but let me see if I can work out why these answers are wrong and why C is right. I am writing this to mostly help myself out, but hopefully whatever I write will be helpful to someone else too. I don't want to be a waste of internet space
Conclusion: If you want to protect your dog from arthritis, you should not neuter your dog until it is full grown.
I think the reason why I got D and E wrong is because I misunderstood what the conclusion was trying to say.
D: Note the conclusion does not say : "If you want to protect your dog from every disease out there and be the the most healthy and have all the benefits in the world, then you should not neuter your dog when it is a puppy." No, the conclusion is simply saying that if you want to protect your dog from arthritis, then you should not do X. So D is wrong because the author is not saying that you should not neuter your dog when it's a puppy because there are no benefits to neutering a dog early. It's a simple conditional argument: If you want to protect your dog from arthritis, don't do something which can increase its risk for arthritis.
E: Notice the conclusion does not say: If you do X, your dog will completely safe from arthritis (mistaken reversal?). Nor does it say: If you want to protect your dog completely and 100 percent from arthritis, then you must do X. You can aim to try to protect yourself from something but at the same time consider the possibility that you are not 100 percent protected. For example, I may not walk down a certain alleyway by myself in order to protect myself from getting robbed. But that does not mean that in doing so I have failed to consider the possibility of getting robbed in another way(for ex., someone could try to steal something from me in a subway when I am not looking). The conclusion just simply gives one method for which to protect your dog from arthritis. It does not necessarily exclude other methods which may be necessary for protecting your dog from arthritis.
C: Is the correct answer because the research focused only on the effects of neutering in the early stage of puppyhood, not the effects on the later stages of puppyhood or teenagehood...or any stage before the "fully grown" stage. So even if the premises are true, the conclusion does not automatically follow. In other words, what if the effects of neutering in the later stages of puppyhood do not include improper bone development or anything which leads to arthritis? Then the conclusion that you should wait until your dog is fully-grown before neutering does not necessarily follow.