22. (B)
Question Type: Unconditional
This is a CANNOT be true question, and hypotheticals from past questions prove to be very useful. Our hypotheticals from #21 prove that (A), (C), and (D) can be true, and #19 proves that (E) can be true. This leaves us with our answer (B), which cannot be true.
Without hypotheticals from past questions we would have to write new hypotheticals making each answer choice true in order to find the one that CANNOT be true. This would take much more time and effort.