The period when the great painted caves at Lascaux and Altamira were occupied by Upper Paleolithic people has been established by carbon-14 dating, but what is much more difficult to determine are the reason for their decoration, the use to which primitive people put the caves, and the meaning of the magnificently depicted animals.
(A) has been established by carbon-14 dating, but what is much more difficult to determine are
(B) has been established by carbon-14 dating, but what is much more difficult to determine is
(C) have been established by carbon-14 dating, but what is much more difficult to determine is
(D) have been established by carbon-14 dating, but what is much more difficult to determine are
(E) are established by carbon-14 dating, but that which is much more difficult to determine is
Here correct ans is (B). But isn't saying "what is" wrong due to the compund subject created at the end by "and". This is a typical case of "Flip it" (SC guide). The subject comes after the verb and would require a plural verb "are".